| Autoimmune thyroiditis presenting as palmoplantar keratoderma. | |
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MedLine Citation:
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PMID: 20300544 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Palmoplantar keratoderma is a heterogeneous group of hereditary and acquired disorders characterized by abnormal thickening of palms and soles. Hypothyroidism is an unusual cause of palmoplantar keratoderma, rarely reported in the literature. We report a case of a 43-year-old woman presented with a 3-month history of a diffuse palmoplantar hyperkeratosis unresponsive to topical keratolytics and corticosteroids. Her past medical and family histories were unremarkable. She complained of recent asthenia, mood changes and constipation. Laboratory evaluation revealed an autoimmune thyroiditis with hypothyroidism. Other causes of acquired palmoplantar keratoderma were excluded. After hormonal replacement therapy institution, a gradual improvement of skin condition was observed. The diagnosis of underlying causes for acquired palmoplantar keratoderma can be a difficult task; however its recognition is essential for successful treatment results. Although a very rare association, hypothyroidism must be suspected in patients with acquired palmoplantar keratoderma, particularly when it occurs in association with systemic symptoms. |
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Authors:
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Sara Lestre; Eva Lozano; Cláudia Meireles; Ana Barata Feio |
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Publication Detail:
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Type: Journal Article Date: 2010-03-14 |
Journal Detail:
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Title: Case reports in medicine Volume: 2010 ISSN: 1687-9635 ISO Abbreviation: Case Report Med Publication Date: 2010 |
Date Detail:
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Created Date: 2010-03-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101512910 Medline TA: Case Report Med Country: United States |
Other Details:
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Languages: eng Pagination: 604890 Citation Subset: - |
Affiliation:
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Dermatology Department, Hospital de Santo António dos Capuchos, 1150-314 Lisboa, Portugal. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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