| Autoimmune thyroid diseases in patients with chronic fasciolosis. | |
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MedLine Citation:
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PMID: 12741079 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The prevalence of autoimmune thyroid diseases and autoantibodies in patients with chronic fasciolosis (CF) was investigated. METHODS: Thyroid function of 32 patients with CF and 72 patients without fasciolosis infection was evaluated biochemically. Thyroid hormones, antithyroglobulin antibodies (TgAb) and antithyroid peroxidase antibodies (TPOAb) were measured. RESULTS: In patients with CF, the prevalences of autoantibodies against thyroid peroxidase and thyroglobulin were 21.9% (7/32) and 15.6% (5/32) respectively. However, thyroid function disorder was identified in only 3 (9.4%) cases. In the control group, TPOAb and TgAb were determined in 2 (2.7%) cases, but no one had thyroid function disorder. The prevalences of thyroid autoantibodies (chi 2: 7.948, p < 0.01) and autoimmune thyroid diseases (chi 2: 4.007, p < 0.05) were significantly higher in the CF group. CONCLUSIONS: The high prevalence of TPOAb and TgAb in CF suggests that patients with CF should be evaluated for autoimmune thyroid disorders at the time of diagnosis and during the follow-up period. |
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Authors:
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Mustafa Demirci; S Ercan Tunc; Namik Delibas; M Numan Tamer; Irfan Altuntas; Metin Korkmaz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Wiener klinische Wochenschrift Volume: 115 ISSN: 0043-5325 ISO Abbreviation: Wien. Klin. Wochenschr. Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-05-13 Completed Date: 2003-10-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 21620870R Medline TA: Wien Klin Wochenschr Country: Austria |
Other Details:
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Languages: eng Pagination: 182-5 Citation Subset: IM |
Affiliation:
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Department of Microbiology and Clinical Microbiology, Faculty of Medicine, Süleyman Demirel University, Isparta, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Autoantibodies / blood* Comorbidity Cross-Sectional Studies Eosinophilia / diagnosis, epidemiology, immunology Fascioliasis / diagnosis, epidemiology*, immunology Female Humans Immunoglobulin G / blood Iodide Peroxidase / immunology* Middle Aged Thyroglobulin / immunology* Thyroiditis, Autoimmune / diagnosis, epidemiology*, immunology |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Immunoglobulin G; 9010-34-8/Thyroglobulin; EC 1.11.1.8/Iodide Peroxidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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