| Autoimmune thyroid diseases in patients with undifferentiated connective tissue disease. | |
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MedLine Citation:
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PMID: 10752498 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Previous data have indicated that organ-specific and non-organ-specific autoimmune diseases may occur in the same patient. We report here our study on the type and prevalence of endocrine autoimmune diseases in undifferentiated connective tissue disease (UCTD). A retrospective analysis revealed five out of 75 UCTD cases (6.6%) with cytology-verified autoimmune thyroiditis (associated with insulin-dependent diabetes mellitus in one case). Other UCTD patients had Graves' disease (one case), non-toxic multinodular goitre (two cases) and central hypothyroidism (one case). In a prospective study, thyroid function was evaluated in 15 consecutive UCTD patients with neither clinical nor laboratory signs of thyroid involvement. Basal and post-TRH stimulation TSH levels were significantly higher in UCTD patients than in healthy subjects. |
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Authors:
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M G Danieli; L Rossetti; P Fraticelli; G Malcangi; I Testa; G Danieli |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Clinical rheumatology Volume: 19 ISSN: 0770-3198 ISO Abbreviation: Clin. Rheumatol. Publication Date: 2000 |
Date Detail:
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Created Date: 2000-05-25 Completed Date: 2000-05-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8211469 Medline TA: Clin Rheumatol Country: BELGIUM |
Other Details:
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Languages: eng Pagination: 42-6 Citation Subset: IM |
Affiliation:
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Institute of Internal Medicine, Hematology and Clinical Immunology, University of Ancona, Italy. eleonora@popcsi.unian.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Antibodies, Antinuclear / immunology Autoantigens / immunology Biopsy, Needle Connective Tissue Diseases / complications*, diagnosis, immunology Diagnosis, Differential Female Fluorescent Antibody Technique Humans Iodide Peroxidase / immunology Iron-Binding Proteins* Male Middle Aged Prospective Studies Radioimmunoassay Retrospective Studies Thyroglobulin / immunology Thyroiditis, Autoimmune / blood, complications*, diagnosis, immunology Thyrotropin / blood |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Antinuclear; 0/Autoantigens; 0/Iron-Binding Proteins; 9002-71-5/Thyrotropin; 9010-34-8/Thyroglobulin; EC 1.11.1.7/TPO protein, human; EC 1.11.1.8/Iodide Peroxidase |
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