| Autoimmune limbic encephalitis. | |
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MedLine Citation:
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PMID: 22034711 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Autoimmune limbic encephalitis is an increasingly recognised cause of cognitive decline and confusion. The typical presentation is with subacute cognitive decline, behavioural disturbance and seizures. Magnetic resonance imaging may show characteristic changes in the medial temporal regions. The diagnosis is confirmed by identification of elevated voltage-gated potassium channel antibody (VGKC-Ab) titres. It is a highly treatable condition, often responding well to intravenous immunoglobulin or steroids. Recognition of autoimmune limbic encephalitis is sometimes delayed--usually because the diagnosis has not been considered--which can result in long-term neurological consequences. |
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Authors:
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Christopher P Derry; Mark D Wilkie; Rustam Al-Shahi Salman; Richard J Davenport |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical medicine (London, England) Volume: 11 ISSN: 1470-2118 ISO Abbreviation: Clin Med Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-31 Completed Date: 2011-11-23 Revised Date: 2012-02-29 |
Medline Journal Info:
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Nlm Unique ID: 101092853 Medline TA: Clin Med Country: England |
Other Details:
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Languages: eng Pagination: 476-8 Citation Subset: IM |
Affiliation:
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Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh. cderry@nhs.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoantibodies
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analysis Autoimmune Diseases of the Nervous System / diagnosis* Cognition Disorders / immunology Diagnosis, Differential Disease Progression Epilepsy, Tonic-Clonic / immunology Fatal Outcome Humans Immunoglobulins, Intravenous / therapeutic use Immunologic Factors / therapeutic use Limbic Encephalitis / diagnosis*, immunology* Magnetic Resonance Imaging Male Middle Aged Potassium Channels, Voltage-Gated / immunology Prognosis |
| Grant Support | |
ID/Acronym/Agency:
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//Medical Research Council |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Immunoglobulins, Intravenous; 0/Immunologic Factors; 0/Potassium Channels, Voltage-Gated |
| Comments/Corrections | |
Comment In:
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Clin Med. 2012 Feb;12(1):95-6
[PMID:
22372238
]
Clin Med. 2012 Feb;12(1):96 [PMID: 22372239 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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