| Autoimmune hepatitis overlapping with primary sclerosing cholangitis. | |
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MedLine Citation:
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PMID: 12322794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of autoimmune hepatitis (AIH) complicated by primary sclerosing cholangitis (PSC) in a 36-year-old woman is reported. AIH overlapping with PSC has been rarely reported, and to the best of our knowledge, there have been no reports in Japan. Based on the criteria for diagnosis of AIH and on typical endoscopic retrograde cholangiograph (ERC) findings, the patient was diagnosed as having AIH overlapping with PSC. Her transaminase levels normalized within 1 month after administration of prednisone, azathioprine and ursodeoxycholic acid, but her cholestatic enzyme level remained elevated. The effect of treatment on the cholestatic features is thought to be an important factor for predicting the prognosis of AIH overlapping with PSC. |
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Authors:
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Junko Takiguchi; Hiromasa Ohira; Tsuyoshi Rai; Shoichiro Shishido; Jun Tojo; Yukio Sato; Reiji Kasukawa; Hiroshi Watanabe; Yuji Funabashi; Hiromi Kumakawa |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 41 ISSN: 0918-2918 ISO Abbreviation: Intern. Med. Publication Date: 2002 Sep |
Date Detail:
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Created Date: 2002-09-26 Completed Date: 2003-03-26 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 696-700 Citation Subset: IM |
Affiliation:
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Second Department of Internal Medicine, Fukushima Medical University School of Medicine. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Autoantibodies / blood Azathioprine / therapeutic use Cholangiopancreatography, Endoscopic Retrograde Cholangitis, Sclerosing / complications*, drug therapy, pathology Female Glucocorticoids / therapeutic use Hepatitis, Autoimmune / complications*, drug therapy, pathology Humans Immunosuppressive Agents / therapeutic use Liver / pathology*, radiography Liver Function Tests Prednisone / therapeutic use Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Glucocorticoids; 0/Immunosuppressive Agents; 446-86-6/Azathioprine; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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