Document Detail


Autoimmune hepatitis in patients with primary Sjögren's syndrome: a series of two-hundred and two patients.
MedLine Citation:
PMID:  20661405     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Based on the revised criteria of the American-European Consensus Group, we retrospectively established the diagnosis of primary or secondary Sjögren's syndrome for 202 patients referred to a Sjögren's syndrome clinic. Of these, 58 patients and 8 patients fulfilled criteria for primary and secondary Sjögren's syndrome, respectively. Of the 58 patients with primary Sjögren's syndrome, one (1.7%) had definite autoimmune hepatitis, as defined by the International Autoimmune Hepatitis Group diagnostic criteria. One additional symptomatic patient who did not fulfill criteria for primary Sjögren's syndrome had definite autoimmune hepatitis. None of the patients with secondary Sjögren's syndrome had definite autoimmune hepatitis. Two (1%) of the 194 patients with primary Sjögren's syndrome or clinical symptoms had primary biliary cirrhosis. These values are lower than those reported by prior studies with smaller patient populations and likely represent a more accurate estimate of the true prevalence of these diseases in patients with primary Sjögren's syndrome.
Authors:
Julie K Karp; Esen K Akpek; Robert A Anders
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-03-25
Journal Detail:
Title:  International journal of clinical and experimental pathology     Volume:  3     ISSN:  1936-2625     ISO Abbreviation:  Int J Clin Exp Pathol     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101480565     Medline TA:  Int J Clin Exp Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  582-6     Citation Subset:  IM    
Affiliation:
Department of Pathology, The Johns Hopkins Hospital, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R01DK081417/DK/NIDDK NIH HHS; R01DK80736/DK/NIDDK NIH HHS

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