Document Detail


Autoimmune thrombocytopenic purpura in partial DiGeorge syndrome: case presentation.
MedLine Citation:
PMID:  21792043     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The absence of an appropriate central tolerance in primary immunodeficiencies favors proliferation of autoreactive lymphocyte clones, causing a greater incidence of autoimmunity. Del 22q11.2 syndrome presents an increased incidence of allergic and autoimmune diseases. One of the most relevant and frequent immune manifestations is autoimmune thrombocytopenia. We present the case of a pediatric patient with autoimmune thrombocytopenia due to the immunological dysregulation observed in partial DiGeorge syndrome.
Authors:
Leticia Hernández-Nieto; Marco Antonio Yamazaki-Nakashimada; Esther Lieberman-Hernández; Sara Elva Espinosa-Padilla
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  33     ISSN:  1536-3678     ISO Abbreviation:  J. Pediatr. Hematol. Oncol.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-27     Completed Date:  2011-09-27     Revised Date:  2011-10-06    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  465-6     Citation Subset:  IM    
Affiliation:
Department of Immunology, Instituto Nacional de Pediatria, Mexico City, Mexico.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Chromosome Deletion
DiGeorge Syndrome / complications*,  immunology*
Female
Humans
Purpura, Thrombocytopenic, Idiopathic / etiology*

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