Document Detail

Autoimmune Hemolytic Anemia and Immune Thrombocytopenia as Unusual Presentations of Childhood Hodgkin Lymphoma: A Case Report and Review of the Literature.
MedLine Citation:
PMID:  22258348     Owner:  NLM     Status:  Publisher    
We discuss an unusual clinical presentation of childhood Hodgkin lymphoma; a 16-year-old girl was referred for Coombs-positive severe anemia, thrombocytopenia, and asymptomatic anterior mediastinal mass. Bone marrow examination showed no evidence of neoplastic disease. Biopsy of the mass was possible only after administration of both intravenous immunoglobulins and steroids resulting in a prompt rise of the platelet count and partial hemoglobin level stabilization. The identification of this clinical picture as a possible complication of an underlying Hodgkin lymphoma presents difficulties in diagnosis and management of the primary condition.
Valerio Cecinati; Fulvia Brugnoletti; Mariella D'Angiò; Maria Chiara De Nicolò; Annalisa De Vellis; Serelina Coluzzi; Anna Maria Testi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-16
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  -     ISSN:  1536-3678     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
*Department of Cellular Biotechnologies and Hematology, Division of Hematology †Department of Transfusion Medicine, Blood Bank, "Sapienza" University, Rome, Italy.
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