Document Detail

Autoimmune enteropathy: a review and update of clinical management.
MedLine Citation:
PMID:  22810979     Owner:  NLM     Status:  MEDLINE    
Autoimmune enteropathy (AIE) is a rare condition characterized by intractable diarrhea, histologic changes on small intestinal biopsy, and failed response to dietary manipulation that also may present with extraintestinal manifestations. In many patients, immunosuppressive therapies are necessary. Although AIE is more common in infants, adult involvement has also been documented. Much of what is known about AIE has been gathered from case reports and small case series; therefore, more research in this evolving field is needed. IPEX (immunodysregulation polyendocrinopathy enteropathy X-linked syndrome) and APECED (autoimmune phenomena, polyendocrinopathy, candidiasis, and ectodermal dystrophy) are systemic forms of AIE.
Nicole M Gentile; Joseph A Murray; Darrell S Pardi
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current gastroenterology reports     Volume:  14     ISSN:  1534-312X     ISO Abbreviation:  Curr Gastroenterol Rep     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-20     Completed Date:  2013-02-12     Revised Date:  2014-02-06    
Medline Journal Info:
Nlm Unique ID:  100888896     Medline TA:  Curr Gastroenterol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  380-5     Citation Subset:  IM    
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MeSH Terms
Autoimmune Diseases* / diagnosis,  physiopathology,  therapy
Immunosuppressive Agents / therapeutic use*
Intestinal Diseases / diagnosis,  immunology*,  therapy
Parenteral Nutrition
Grant Support
Reg. No./Substance:
0/Immunosuppressive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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