Document Detail


Autogenous fat injection for vocal fold atrophy.
MedLine Citation:
PMID:  12736747     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Autogenous fat augmentation for glottic insufficiency has been used previously in patient treatment regimes. However, relatively little information is currently available regarding the effectiveness of fat injection for patients with vocal fold atrophy who have complete glottal closure (VFACGC). This paper compares, in retrospect, the efficiency of fat injection after surgery in patients with VFACGC (n=21). The perceptual acoustic and phonatory functions and videolaryngostroboscopic data were evaluated before and after fat augmentation was performed on 13 patients. Mean follow-up time was 9.5 months. Fifteen patients displayed excellent results, four experienced post-procedure failure, and two were unavailable for follow-up analysis. The majority of VFACGC patients (71%) also suffered from muscular tension dysphonia (MTD) preoperatively. The procedure also resolved the MTD in half (54%) of the patients in this study. Perceptual rating showed significant improvement in grade, roughness and breathiness (P<0.05). The videolaryngostroboscopic rating showed significant improvements in vocal fold edge linearity (P<0.01), vocal fold vibration amplitude and mucosal wave excursion (P<0.05). VFACGC is commonly misdiagnosed as MTD and is, therefore, unresponsive to speech therapy that is targeted to the latter. Fat injection is an effective autogenous implant and should be considered as an option in the treatment of patients with VFACGC. Although fat re-absorption was identified as a problem, repeating the procedure could be considered to minimize the effect of such.
Authors:
Ming-Wang Hsiung; Yaoh-Shiang Lin; Wan-Fu Su; Hsing-Won Wang
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2003-05-08
Journal Detail:
Title:  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery     Volume:  260     ISSN:  0937-4477     ISO Abbreviation:  Eur Arch Otorhinolaryngol     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-10-30     Completed Date:  2004-05-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9002937     Medline TA:  Eur Arch Otorhinolaryngol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  469-74     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, Tri-Service General Hospital, National Defense Medical Center, No 325, Chenggung Road, Section 2, 114 Taipei, Taiwan ROC. hsiunm01kimo@yahoo.com.tw
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / transplantation*
Adult
Aged
Atrophy / surgery
Female
Follow-Up Studies
Humans
Injections
Laryngoscopy
Male
Middle Aged
Patient Selection
Transplantation, Autologous
Vocal Cords / pathology*,  surgery
Voice Disorders / etiology,  physiopathology,  surgery*

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