| Autogenous bone graft: basic science and clinical implications. | |
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MedLine Citation:
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PMID: 22337435 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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ABSTRACT: No single biomaterial is optimum for every craniomaxillofacial application. Instead, surgeons should consider the advantages and disadvantages of each alternative in a given clinical situation, and select the material with lowest overall cost and morbidity, and the highest likelihood of success. Autogenous bone is still considered the gold standard for most applications; it becomes vascularized and osseointegrates with surrounding bone, thus minimizing the risk of infection, dislodgement, or break-down. Limitations include added operative time for graft harvest, donor site morbidity, graft resorption, molding challenges, and limited availability, especially in the pediatric population. Numerous alternatives to bone graft have become available to address these limitations; unfortunately, most of these products are expensive, do not osseointegrate, and have unpredictable biologic activity. Understanding the physiologic behavior of autogenous bone graft can help clarify the indications for its use and provide a conceptual framework for achieving the best possible outcome when this alternative is chosen. |
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Authors:
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Gary F Rogers; Arin K Greene |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of craniofacial surgery Volume: 23 ISSN: 1536-3732 ISO Abbreviation: J Craniofac Surg Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-02-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9010410 Medline TA: J Craniofac Surg Country: United States |
Other Details:
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Languages: eng Pagination: 323-7 Citation Subset: D |
Affiliation:
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From the *Division of Plastic and Reconstructive Surgery, Children's National Medical Center, Washington, District of Columbia; and †Department of Plastic and Oral Surgery, Children's Hospital Boston, Boston, Massachusetts. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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