Document Detail


Autocovariance Structures for Radial Averages in Small Angle X-Ray Scattering Experiments.
MedLine Citation:
PMID:  23355752     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Small-angle X-ray scattering (SAXS) is a technique for obtaining low-resolution structural information about biological macromolecules, by exposing a dilute solution to a high-intensity X-ray beam and capturing the resulting scattering pattern on a two-dimensional detector. The two-dimensional pattern is reduced to a one-dimensional curve through radial averaging; that is, by averaging across annuli on the detector plane. Subsequent analysis of structure relies on these one-dimensional data. This paper reviews the technique of SAXS and investigates autocorrelation structure in the detector plane and in the radial averages. Across a range of experimental conditions and molecular types, spatial autocorrelation in the detector plane is present and is well-described by a stationary kernel convolution model. The corresponding autocorrelation structure for the radial averages is non-stationary. Implications of the autocorrelation structure for inference about macromolecular structure are discussed.
Authors:
F Jay Breidt; Andreea Erciulescu; Mark van der Woerd
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-18
Journal Detail:
Title:  Journal of time series analysis / a journal sponsored by the Bernoulli Society for Mathematical Statistics and Probability     Volume:  33     ISSN:  0143-9782     ISO Abbreviation:  J Time Ser Anal     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101574749     Medline TA:  J Time Ser Anal     Country:  -    
Other Details:
Languages:  ENG     Pagination:  704-717     Citation Subset:  -    
Affiliation:
Department of Statistics, Colorado State University.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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