| Autoantibodies to the core proteins of hnRNPs. | |
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MedLine Citation:
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PMID: 3282919 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A novel autoantibody reacting the the core polypeptides of hnRNP particles has been detected in the serum of a patient with systemic lupus erythematosus (SLE) and Sjögren's syndrome manifestations. Immunoblot analysis, using either rat liver or HeLa nuclear extracts as the antigen source, demonstrated that the autoantibody interacts with a specific subgroup of the core polypeptides of hnRNP particles, namely A2, B1 and B2, but not with A1, C1 and C2. |
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Authors:
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A Dangli; A Guialis; E Vretou; C E Sekeris |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: FEBS letters Volume: 231 ISSN: 0014-5793 ISO Abbreviation: FEBS Lett. Publication Date: 1988 Apr |
Date Detail:
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Created Date: 1988-06-02 Completed Date: 1988-06-02 Revised Date: 2008-09-13 |
Medline Journal Info:
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Nlm Unique ID: 0155157 Medline TA: FEBS Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 118-24 Citation Subset: IM |
Affiliation:
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Biological Research Center, National Hellenic Research Foundation, Athens, Greece. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Autoantibodies / isolation & purification* Cell Nucleus / immunology* Chromatography, Affinity Fluorescent Antibody Technique Hela Cells / immunology Heterogeneous-Nuclear Ribonucleoprotein Group A-B* Heterogeneous-Nuclear Ribonucleoprotein Group C* Heterogeneous-Nuclear Ribonucleoproteins Humans Liver / immunology* Lupus Erythematosus, Systemic / immunology Rats Ribonucleoproteins / immunology* Sjogren's Syndrome / immunology |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/C1 HNRNP; 0/HNRNPC protein, human; 0/Heterogeneous-Nuclear Ribonucleoprotein Group A-B; 0/Heterogeneous-Nuclear Ribonucleoprotein Group C; 0/Heterogeneous-Nuclear Ribonucleoproteins; 0/Ribonucleoproteins; 0/heterogeneous nuclear ribonucleoprotein A2-B1; 0/hnRNP A1 |
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