Document Detail

Auto-positive end-expiratory pressure during one-lung ventilation using a double-lumen endobronchial tube.
MedLine Citation:
PMID:  8610857     Owner:  NLM     Status:  MEDLINE    
The present study was undertaken to investigate the possible relationships between the magnitude of autopositive end-expiratory pressure (auto-PEEP) and measured PaO2 during one-lung ventilation (OLV). Forty-one adults received OLV anesthesia using a tidal volume of 8 mL/kg and a respiratory rate of 12 breaths/min. Auto-PEEP was quantified using an end-expiratory port occlusion method. During two-lung ventilation (2LV), auto-PEEP was observed in 18 of 41 patients and ranged from 0.5 to 2.5 cm H2O. During OLV, auto-PEEP was observed in 34 of 41 patients and ranged from 0.5 to 10 cm H2O. The mean (+/- SD) value of auto-PEEP was significantly higher during OLV than during 2LV (3.2 +/- 3.3 cm H2O versus 0.5 +/- 0.7 cm H2O, P < 0.0001). Auto-PEEP during OLV correlated inversely with preoperative forced expiratory volume in 1 s/forced vital capacity (y = 12.5 - 0.13x, r = -.05, P < 0.005). During OLV, there was no significant correlation between auto-PEEP and measured PaO2. These findings confirm that many patients do not exhale completely to functional residual capacity during OLV.
K Yokota; T Toriumi; A Sari; S Endou; M Mihira
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  82     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-05-24     Completed Date:  1996-05-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1007-10     Citation Subset:  AIM; IM    
Department of Anesthesiology and Intensive Care Medicine, Kawasaki Medical School, Okayama, Japan.
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MeSH Terms
Aged, 80 and over
Equipment Design
Forced Expiratory Volume
Functional Residual Capacity
Intubation, Intratracheal / instrumentation*
Lung / physiology*
Middle Aged
Oxygen / blood
Positive-Pressure Respiration*
Tidal Volume
Vital Capacity
Reg. No./Substance:
Comment In:
Anesth Analg. 1996 Nov;83(5):1131   [PMID:  8895305 ]

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