Document Detail

Auto-immune Addison's disease associated with hyperprolactinaemia.
MedLine Citation:
PMID:  6096047     Owner:  NLM     Status:  MEDLINE    
Four cases of auto-immune Addison's disease are reported in association with hyperprolactinaemia. Two of the females had galactorrhoea. In three cases complete resolution of hyperprolactinaemia occurred with corticosteroid replacement, but it was only partial in the fourth. We suggest that hyperprolactinaemia was due to cortisol deficiency operating directly or indirectly at the level of the pituitary. These data support the animal and in vitro evidence for the influence of corticosteroids on prolactin release.
E G Lever; C G McKerron
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical endocrinology     Volume:  21     ISSN:  0300-0664     ISO Abbreviation:  Clin. Endocrinol. (Oxf)     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1985-02-15     Completed Date:  1985-02-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0346653     Medline TA:  Clin Endocrinol (Oxf)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  451-7     Citation Subset:  IM    
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MeSH Terms
Addison Disease / blood*,  drug therapy,  immunology
Adrenocorticotropic Hormone / blood
Autoantibodies / analysis
Hydrocortisone / blood,  therapeutic use
Pituitary Gland / immunology
Prolactin / blood*
Reg. No./Substance:
0/Autoantibodies; 50-23-7/Hydrocortisone; 9002-60-2/Adrenocorticotropic Hormone; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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