| Autism in Angelman syndrome: an exploration of comorbidity. | |
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MedLine Citation:
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PMID: 15165432 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim was to explore the comorbidity between Angelman syndrome and autism spectrum disorders (ASDs). Identification of autism in children with Angelman syndrome presents a diagnostic challenge. In the present study, 16 children with Angelman syndrome, all with a 15q11-13 deletion, were examined for ASDs. Thirteen children with Angelman syndrome received an ADOS-G algorithm classification of ASD; the remaining three were outside the autistic spectrum. Ten fulfilled the criteria for autism, and three for PDD-NOS. The 10 children with Angelman syndrome and comorbid autism were compared with eight children with only autism regarding their social and communicative skills. The results indicated that Angelman syndrome is better understood in terms of developmental delay, and autism in terms of developmental deviance. It is concluded that autism might have been overdiagnosed due to the extremely low mental age of the children with Angelman syndrome. |
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Authors:
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Anegen Trillingsgaard; John R ØStergaard |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Autism : the international journal of research and practice Volume: 8 ISSN: 1362-3613 ISO Abbreviation: Autism Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-05-28 Completed Date: 2004-09-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9713494 Medline TA: Autism Country: England |
Other Details:
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Languages: eng Pagination: 163-74 Citation Subset: IM |
Affiliation:
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Psychiatric Hospital for Children and Adolescents, University Hospital, Aarhus, Denmark. Atr@buh.aaa.dk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Angelman Syndrome / complications* Autistic Disorder / complications* Child Child Development Chromosomes, Human, Pair 15* Communication Comorbidity Developmental Disabilities* Female Humans Male Social Behavior |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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