Document Detail


Australian encephalitis in Western Australia, 1978-1991.
MedLine Citation:
PMID:  8386796     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To review the various clinical manifestations of Murray Valley encephalitis (MVE) or Kunjin virus encephalitis in patients in Western Australia. DESIGN: Review of clinical records, 1978 to 1991. PATIENTS: Of 26 reported cases of Australian encephalitis, four were excluded from study because the patient's symptoms were not definitely associated with MVE virus or Kunjin virus infection. Two further cases of MVE were not reviewed as case records were not available. Of the remaining 20 patients, 18 had MVE and two had Kunjin virus encephalitis. RESULTS: Sixteen cases were in the Kimberley, a tropical region where the viruses are endemic. Four were in the subtropical Pilbara and Gascoyne regions. Thirteen of the 20 cases were in Aborigines, of whom 11 were children. The seven non-Aboriginal patients were adults. Seventeen of 20 cases were in males. The range of neurological disease and outcome was similar to that in previously reported cases, with convulsions, brainstem disease or respiratory failure in severe and fatal cases, and involvement of the spinal cord, cranial nerve or cerebellum in the moderate cases. One mild cases without neurological involvement was caused by Kunjin virus. CONCLUSIONS: The poor outcome in young Aboriginal children indicated that disease resulting from exposure early in life was more likely to be severe. The disease in adults, irrespective of facial background, was similar to that in cases reported previously from south-eastern Australia, but generally milder.
Authors:
J S Mackenzie; D W Smith; A K Broom; M R Bucens
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Medical journal of Australia     Volume:  158     ISSN:  0025-729X     ISO Abbreviation:  Med. J. Aust.     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-05-25     Completed Date:  1993-05-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0400714     Medline TA:  Med J Aust     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  591-5     Citation Subset:  IM    
Affiliation:
Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Child, Preschool
Encephalitis / epidemiology*,  physiopathology
Female
Flavivirus*
Humans
Infant
Male
Oceanic Ancestry Group
Togaviridae Infections / epidemiology*,  physiopathology
Western Australia / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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