| Aureobasidin, new antifouling metabolite from marine-derived fungus Aureobasidium sp. | |
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MedLine Citation:
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PMID: 19413119 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two antifouling compounds, aureobasidin (1), a new ester with an unusual 4,6-dihydroxydecanoic acid residue, and (3R,5S)-3,5-dihydroxydecanoic acid (2), were isolated from the marine-derived fungus Aureobasidium sp., in addition to (5R,3Z)-5-hydroxydec-3-enoic acid (3) and (R)-3-hydroxydecanoic acid (4). The structures were unambiguously established by IR, 1D and 2D NMR spectroscopic and mass spectral data. Compounds 1-3 were found to be active against Bacillus subtilis, Escherichia coli and Staphyllococcus aureus. Compound 3 showed fungistatic activity against Candida albicans. |
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Authors:
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Ahmed Abdel-Lateff; Ehab S Elkhayat; Mostafa A Fouad; Tatsufumi Okino |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Natural product communications Volume: 4 ISSN: 1934-578X ISO Abbreviation: Nat Prod Commun Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-05-05 Completed Date: 2009-06-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101477873 Medline TA: Nat Prod Commun Country: United States |
Other Details:
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Languages: eng Pagination: 389-94 Citation Subset: IM |
Affiliation:
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Department ofPharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ascomycota
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chemistry* Bacillus subtilis / drug effects Candida albicans / drug effects Decanoic Acids / analysis*, isolation & purification*, pharmacology Escherichia coli / drug effects Esters / analysis*, isolation & purification*, pharmacology Magnetic Resonance Spectroscopy Molecular Structure Staphylococcus aureus / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Decanoic Acids; 0/Esters |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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