| Augmentation of coronary blood flow by intra-aortic balloon pumping in patients after coronary angioplasty. | |
| | |
MedLine Citation:
|
PMID: 8425297 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Controversy exists regarding the ability of intra-aortic balloon pumping to increase coronary blood flow in patients with obstructive coronary artery disease. To assess the effects of intra-aortic balloon pumping on coronary hemodynamics, we measured coronary blood flow velocity with a 0.018-in. Doppler-tipped angioplasty guide wire in 15 patients who received an intra-aortic balloon pump for typical clinical indications. METHODS AND RESULTS: Intra-aortic balloon pumping augmented diastolic pressure 83 +/- 35%. In nine patients before angioplasty, peak diastolic coronary flow velocity beyond the stenosis (mean diameter narrowing, 95 +/- 7%) was 5.3 +/- 9.6 cm/sec and was unaffected by intra-aortic balloon pumping. After angioplasty, the improved coronary luminal diameter narrowing (n = 12; mean narrowing, 18 +/- 12%) was associated with increased distal diastolic flow velocity integral and peak diastolic and mean velocities (13.3 +/- 8.4 units: 36.4 +/- 18.3 and 24.0 +/- 11.4 cm/sec, respectively; all p < 0.01 versus before angioplasty), which were further augmented (36 +/- 37%, 54 +/- 49%, and 26 +/- 17%, respectively; all p < 0.01) with intra-aortic balloon pumping. Intra-aortic balloon pumping did not significantly increase the distal systolic velocity integral (10 +/- 59%) or peak systolic velocity (3 +/- 33%). Similar degrees of balloon pump augmentation of distal coronary flow velocity values were observed in five angiographically normal reference arteries in four patients. CONCLUSIONS: These data demonstrate lack of significant flow improvement beyond most critical stenoses with intra-aortic balloon pumping and the unequivocal restoration and intra-aortic balloon pump-mediated augmentation of both proximal and distal coronary blood flow velocities after amelioration of severe coronary obstructions in patients after successful coronary angioplasty. |
| | |
Authors:
|
M J Kern; F Aguirre; R Bach; T Donohue; R Siegel; J Segal |
Related Documents
:
|
14659857 - Fractional shortening-velocity ratio for assessment of aortic stenosis severity in pati... 20435207 - Hemodynamic results and changes in myocardial function after transcatheter aortic valve... 12962417 - Successful emergency aortic valve replacement following percutaneous cardiopulmonary su... 6601937 - Aortic valve replacement and coronary bypass in patients with severe stenosis of the le... 18542937 - Impaired heart rate variability and altered cardiac sympathovagal balance after antidep... 21228787 - Obesity-related adjunctive systo-diastolic ventricular dysfunction in patients with hyp... |
Publication Detail:
|
Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Circulation Volume: 87 ISSN: 0009-7322 ISO Abbreviation: Circulation Publication Date: 1993 Feb |
Date Detail:
|
Created Date: 1993-03-03 Completed Date: 1993-03-03 Revised Date: 2010-03-24 |
Medline Journal Info:
|
Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 500-11 Citation Subset: AIM; IM |
Affiliation:
|
Department of Internal Medicine, St. Louis University, Mo. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angioplasty, Transluminal, Percutaneous Coronary* Cineangiography Coronary Angiography Coronary Circulation* Coronary Disease / physiopathology, radiography, therapy* Female Hemodynamics Humans Intra-Aortic Balloon Pumping* Male Middle Aged Postoperative Period |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Radiofrequency endocardial catheter ablation of accessory atrioventricular pathway atrial insertion ...
Next Document: Direct comparison of [13N]ammonia and [15O]water estimates of perfusion with quantification of regio...