Document Detail


Audiological evaluation of twenty patients receiving pentoxifylline and prednisone after sudden deafness: prospective study.
MedLine Citation:
PMID:  14763324     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Idiopathic sudden deafness is defined as sudden sensorineural hearing loss of undetermined etiology. As a consequence, various treatments have been developed for this disorder. Our study evaluated the effectiveness of pentoxifylline and prednisone in such treatment. We analyzed this treatment's results in our patients through conventional audiograms, and speech audiometry was performed in the acute stage and during the treatment. We diagnosed idiopathic sudden hearing loss in 20 patients (8 female and 12 male). The left ear was involved in 9 patients and the right in 11. All patients had been examined by us within 15 days from the onset of hearing loss. We compared the hearing threshold results in the different periods in this prospective study.
Authors:
Flávia Alencar de Barros; Norma Oliveira Penido; Hugo Valter Lisboa Ramos; Maura Lígia Sanchez; Yotaka Fukuda
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The international tinnitus journal     Volume:  9     ISSN:  0946-5448     ISO Abbreviation:  Int Tinnitus J     Publication Date:  2003  
Date Detail:
Created Date:  2004-02-06     Completed Date:  2004-03-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9612993     Medline TA:  Int Tinnitus J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  17-22     Citation Subset:  IM    
Affiliation:
Federal University of São Paulo-Paulista Medical School, Brazil. flaviaalencar@uol.com.br
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Inflammatory Agents / therapeutic use*
Audiometry, Pure-Tone / methods
Audiometry, Speech / methods
Female
Hearing Loss, Sudden / diagnosis,  drug therapy*
Humans
Male
Pentoxifylline / therapeutic use*
Prednisone / therapeutic use*
Severity of Illness Index
Speech Perception / physiology*
Tinnitus / diagnosis,  epidemiology
Vasodilator Agents / therapeutic use*
Vertigo / diagnosis,  epidemiology
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Vasodilator Agents; 53-03-2/Prednisone; 6493-05-6/Pentoxifylline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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