| Atypical teratoid/rhabdoid tumor arising from the third cranial nerve. | |
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MedLine Citation:
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PMID: 18769285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An otherwise healthy 6-week-old girl who presented with an isolated left third cranial nerve palsy underwent MRI that revealed an enhancing mass intrinsic to the left third cranial nerve. Rapid enlargement of the lesion over 1 month led to subtotal neurosurgical resection of an atypical teratoid/rhabdoid tumor (AT/RT), a rare, highly aggressive malignancy of infancy closely related histologically to medulloblastoma and primitive neuroectodermal tumor. Despite aggressive chemotherapy, the patient died within 6 months of presentation. This is the first report of an AT/RT presenting as an isolated third cranial nerve palsy caused by tumor arising from within the nerve. |
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Authors:
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Charles C Wykoff; Byron L Lam; Carole D Brathwaite; Jaclyn A Biegel; Craig A McKeown; Marc K Rosenblum; Heather B Allewelt; David I Sandberg |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society Volume: 28 ISSN: 1536-5166 ISO Abbreviation: J Neuroophthalmol Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-09-04 Completed Date: 2009-01-08 Revised Date: 2011-03-24 |
Medline Journal Info:
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Nlm Unique ID: 9431308 Medline TA: J Neuroophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 207-11 Citation Subset: IM |
Affiliation:
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Bascom Palmer Eye Institute, University of Miami Miller School of Medicine and Miami Children's Hospital, Miami, Florida 33136, USA. cwykoff@med.miami.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Combined Chemotherapy Protocols
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administration & dosage Cranial Nerve Neoplasms / pathology*, physiopathology, surgery Disease Progression Fatal Outcome Female Humans Hydrocephalus / etiology Infant Magnetic Resonance Imaging Meningeal Carcinomatosis / etiology Mesencephalon / pathology, surgery Neoplasm Invasiveness / pathology Neoplasm Recurrence, Local / pathology Neurosurgical Procedures Oculomotor Nerve / pathology*, physiopathology, surgery Oculomotor Nerve Diseases / pathology*, physiopathology, surgery Rhabdoid Tumor / pathology*, physiopathology, surgery Subarachnoid Space / pathology Teratoma / pathology*, physiopathology, surgery Treatment Failure Tumor Markers, Biological / analysis, metabolism |
| Grant Support | |
ID/Acronym/Agency:
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CA46274/CA/NCI NIH HHS; P30-EY014801/EY/NEI NIH HHS; R01 CA046274-17A2/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Tumor Markers, Biological |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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