| Atypical reversible posterior leukoencephalopathy syndrome in thrombotic thrombocytopenic purpura. | |
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MedLine Citation:
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PMID: 18981640 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 32-year-old man with an atypical form of reversible leukoencephalopathy syndrome (RPLS) caused by thrombotic thrombocytopenic purpura (TTP) is reported. In this particular case, a timely diagnosis of TTP was established primarily on the clinical findings, which led to the early initiation of plasmapheresis and resulted in excellent clinical recovery. The pathophysiological aspects of the relationship between TTP and RPLS are discussed in light of the clinical and radiological features (including diffusion- and perfusion-weighted magnetic resonance imaging studies) of this case. The mechanism for TTP-associated, or TTP-induced, leukoencephalopathy is suggested to be independent of hypertension and vasoconstriction. TTP-associated endothelial injury can play a major role as the inciting mechanism for the development of RPLS. |
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Authors:
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Demet Funda Bas; Kader Karli Oguz; Mehmet Akif Topcuoglu |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-11-04 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 47 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2008 |
Date Detail:
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Created Date: 2008-11-04 Completed Date: 2009-06-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 1931-4 Citation Subset: IM |
Affiliation:
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Department of Neurology, Hacettepe University Hospitals, Ankara, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Humans Male Posterior Leukoencephalopathy Syndrome / complications*, diagnosis*, therapy Purpura, Thrombotic Thrombocytopenic / complications*, diagnosis*, therapy |
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