Document Detail


Atypical response to treatment in linear IgA bullous dermatosis of childhood: Revision of literature.
MedLine Citation:
PMID:  21696685     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A three-year-old boy presented with 2 months of worsening skin lesions characterized by multiple clear vesicles and bullae. The histopathological and immunohistochemical examinations revealed changes consistent with linear IgA bullous dermatosis of childhood. Treatment with dapsone and prednisolone resulted in gradual clinical improvement. However, within a week of therapy he presented with diabetic ketoacidosis, the onset of type I diabetes mellitus. Since then, keeping this child asymptomatic has been a challenge. This case emphasizes the importance of close monitoring of patients taking systemic corticosteroids; the coexistence of other immune mediated conditions may influence the success of treatment.
Authors:
Susana Moleiro; Vera Santos; Manuela Calha; Graça Pessoa
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-15
Journal Detail:
Title:  Dermatology online journal     Volume:  17     ISSN:  1087-2108     ISO Abbreviation:  -     Publication Date:  2011  
Date Detail:
Created Date:  2011-6-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  5     Citation Subset:  -    
Affiliation:
Hospital de Faro.
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