Document Detail

Atypical herpes type 2 encephalitis associated with normal MRI imaging.
MedLine Citation:
PMID:  12810797     Owner:  NLM     Status:  MEDLINE    
We describe a case of chronic atypical herpes simplex type 2 encephalitis in an immunocompromised 68 year old man presenting with headache and cognitive changes without focal neurological or MRI findings. To our knowledge this is the first described case of herpes simplex encephalitis associated with normal MRI brain imaging and non-focal neurological examination. This further expands the range of clinical presentations that may be associated with herpes simplex encephalitis and emphasises the value of PCR for herpes simplex virus in the investigation of encephalitis regardless of imaging findings.
N A Harrison; B K MacDonald; G Scott; R Kapoor
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  74     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-06-17     Completed Date:  2003-07-22     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  974-6     Citation Subset:  IM    
Psychiatry, Maudsley Hospital, Denmark Hill, London, UK.
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MeSH Terms
Brain / pathology
Cognition Disorders / etiology
DNA, Viral / analysis
Encephalitis, Herpes Simplex / pathology*
Headache / etiology
Herpesvirus 2, Human / pathogenicity*
Immunocompromised Host
Magnetic Resonance Imaging
Polymerase Chain Reaction
Reg. No./Substance:
0/DNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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