| Atypical hearing loss in women with breast cancer receiving adjuvant treatment. | |
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MedLine Citation:
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PMID: 16135407 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There are no reports of adjuvant treatments for early breast cancer causing hearing loss. Yet in this exploratory study 14/16 women who had received Fluorouracil, Epirubicin and Cyclophosphamide (FEC) chemotherapy regimen, 11 of whom also received endocrine treatment, had reduced hearing sensitivity, with 9/16 being atypical. It is not clear whether this finding is related to oestrogen reduction and/or ototoxicity but a more detailed investigation in this area is warranted given the large number of women with breast cancer who receive adjuvant treatments. |
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Authors:
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V Jenkins; H Beveridge; R Low; S Mitra |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2005-08-30 |
Journal Detail:
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Title: Breast (Edinburgh, Scotland) Volume: 15 ISSN: 0960-9776 ISO Abbreviation: Breast Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-06-12 Completed Date: 2006-08-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9213011 Medline TA: Breast Country: Scotland |
Other Details:
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Languages: eng Pagination: 448-51 Citation Subset: IM |
Affiliation:
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Cancer Research UK Psychosocial Oncology Group, Brighton and Sussex Medical School, University of Sussex, Falmer, East Sussex, and Department of Audiology, Royal Sussex County Hospital, Brighton, UK. val@sussex.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antineoplastic Combined Chemotherapy Protocols / adverse effects* Audiometry, Pure-Tone Breast Neoplasms / drug therapy* Chemotherapy, Adjuvant Female Hearing Loss / chemically induced* Humans Middle Aged Pilot Projects |
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