Document Detail

Atypical fibroxanthoma of the skin and the lower lip in xeroderma pigmentosum.
MedLine Citation:
PMID:  10971340     Owner:  NLM     Status:  MEDLINE    
Xeroderma pigmentosum (XP) is a rare, usually autosomal recessive disorder related to DNA repair defects. Atypical fibroxanthoma (AFX) is a pleomorphic tumour that occurs infrequently on the limbs and trunk in children. We report a child with XP who presented with AFX of the facial skin and the lower lip. The diagnosis of AFX was confirmed using histological and immunohistochemical techniques. We discuss the possibility that ultraviolet-induced damage might be implicated in the pathogenesis of AFX.
F H Dilek; N Akpolat; A Metin; S Ugras
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  143     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2000-10-24     Completed Date:  2000-10-24     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  618-20     Citation Subset:  IM    
Department of Pathology, Kocatepe University School of Medicine, Afyon, Turkey.
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MeSH Terms
Carcinoma, Squamous Cell / pathology
Child, Preschool
Diagnosis, Differential
Hemangioma, Capillary / pathology
Histiocytoma, Benign Fibrous / pathology*
Lip Neoplasms / pathology*
Neoplasms, Multiple Primary / pathology*
Skin Neoplasms / pathology*
Xeroderma Pigmentosum / pathology*

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