| Atypical and disparate presentations of laryngeal sarcoidosis. | |
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MedLine Citation:
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PMID: 21049851 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sarcoidosis is a multisystem chronic granulomatous disease of unknown cause that typically affects patients between 20 and 40 years of age. Laryngeal involvement most frequently involves the supraglottis and presents with dyspnea. We present a retrospective review of 4 patients with previously undiagnosed sarcoidosis who presented with atypical signs and symptoms of sarcoidosis: dysphonia with isolated vocal fold involvement; cough and globus pharyngeus; pediatric sarcoidosis; and severe bilateral vocal fold paresis and dysphagia. Our aim is to highlight disparate presentations of laryngeal sarcoidosis, as well as the treatment options. Laryngeal sarcoidosis may present with atypical signs and symptoms and occasionally presents in pediatric patients. A high degree of suspicion is necessary for a correct diagnosis in these patients. Early diagnosis and proper management of laryngeal sarcoidosis is important, as the symptoms are debilitating and possibly life-threatening. Treatment may consist of local and systemic chemotherapy, and adjunctive procedures. |
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Authors:
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Ross M Mayerhoff; Michael J Pitman |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Annals of otology, rhinology, and laryngology Volume: 119 ISSN: 0003-4894 ISO Abbreviation: Ann. Otol. Rhinol. Laryngol. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-11-05 Completed Date: 2010-11-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0407300 Medline TA: Ann Otol Rhinol Laryngol Country: United States |
Other Details:
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Languages: eng Pagination: 667-71 Citation Subset: AIM; IM |
Affiliation:
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Stony Brook University School of Medicine, Stony Brook, New York, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Child Female Humans Laryngeal Diseases / diagnosis*, drug therapy Middle Aged Retrospective Studies Sarcoidosis / diagnosis*, drug therapy Steroids / therapeutic use Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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