Document Detail


Atypical and disparate presentations of laryngeal sarcoidosis.
MedLine Citation:
PMID:  21049851     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sarcoidosis is a multisystem chronic granulomatous disease of unknown cause that typically affects patients between 20 and 40 years of age. Laryngeal involvement most frequently involves the supraglottis and presents with dyspnea. We present a retrospective review of 4 patients with previously undiagnosed sarcoidosis who presented with atypical signs and symptoms of sarcoidosis: dysphonia with isolated vocal fold involvement; cough and globus pharyngeus; pediatric sarcoidosis; and severe bilateral vocal fold paresis and dysphagia. Our aim is to highlight disparate presentations of laryngeal sarcoidosis, as well as the treatment options. Laryngeal sarcoidosis may present with atypical signs and symptoms and occasionally presents in pediatric patients. A high degree of suspicion is necessary for a correct diagnosis in these patients. Early diagnosis and proper management of laryngeal sarcoidosis is important, as the symptoms are debilitating and possibly life-threatening. Treatment may consist of local and systemic chemotherapy, and adjunctive procedures.
Authors:
Ross M Mayerhoff; Michael J Pitman
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Annals of otology, rhinology, and laryngology     Volume:  119     ISSN:  0003-4894     ISO Abbreviation:  Ann. Otol. Rhinol. Laryngol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-11-05     Completed Date:  2010-11-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0407300     Medline TA:  Ann Otol Rhinol Laryngol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  667-71     Citation Subset:  AIM; IM    
Affiliation:
Stony Brook University School of Medicine, Stony Brook, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Child
Female
Humans
Laryngeal Diseases / diagnosis*,  drug therapy
Middle Aged
Retrospective Studies
Sarcoidosis / diagnosis*,  drug therapy
Steroids / therapeutic use
Young Adult
Chemical
Reg. No./Substance:
0/Steroids

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