Document Detail


Atypical cilia in the respiratory tract of common marmosets (Callithrix jacchus) with and without concurrent lung disease.
MedLine Citation:
PMID:  24102386     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
ABSTRACT Ciliated cells of the respiratory epithelium play an essential role in the mechanisms of mucociliary clearance, and ultrastructural alterations of cilia are known to be associated with respiratory disease. The aim of this study was to evaluate the presence of ciliary changes in common marmosets (Callithrix jacchus) of different age groups and to compare healthy animals with animals suffering from subclinical chronic inflammatory pulmonary lesions. Therefore, samples of different sites of the tracheobronchial tree from 24 common marmosets were investigated by transmission electron microscopy. Ciliary alterations were present in all animals and were represented by compound cilia ("bulging/adhesive type"), extramatrix, extratubuli, and disorientation of the microtubular arrangement. Ciliary alterations affected less than 1% of cilia (average 0.06%-0.55%) with no statistically significant differences between age groups, sample localizations, or healthy and sick animals. The study results suggest that ciliary alterations of secondary nature are a common background finding in common marmosets with individual variability in abundance and have to be considered when interpreting ultrastructural data from respiratory studies.
Authors:
Rebecca Marie Hoffmann; Franz-Josef Kaup; Martina Bleyer
Related Documents :
21325306 - Understanding testosterone variation in a tropical lek-breeding bird.
14627926 - Optimal resistance training: comparison of delorme with oxford techniques.
15995266 - The interaction of aging and 10 years of racing on ultraendurance running performance.
23494666 - Decline in cytochrome c oxidase activity in rat-brain mitochondria with aging. role of ...
15140536 - Prevalence and prognosis of subjects with brugada-type ecg pattern in a young and middl...
15149406 - Variable selection in platanthera bifolia (orchidaceae): phenotypic selection differed ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-10-8
Journal Detail:
Title:  Experimental lung research     Volume:  -     ISSN:  1521-0499     ISO Abbreviation:  Exp. Lung Res.     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-10-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8004944     Medline TA:  Exp Lung Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Pathology Unit, German Primate Center , Kellnerweg 4, 37077 Goettingen , Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Correlations between functional performance, health-related quality of life, and parental impact on ...
Next Document:  Brain activation during speech perception in a patient with a massive left hemisphere infarction.