Document Detail

Atypical bone metastasis and radiation changes in a colon cancer: a case report and a review of the literature.
MedLine Citation:
PMID:  11386465     Owner:  NLM     Status:  MEDLINE    
We report a unique case of skeletal metastasis with prominent soft tissue extension from a colon cancer in a 44-year-old male patient. Four years after the diagnosis of colon cancer, plain radiographic examinations revealed a prominent soft tissue mass associated with cortical destruction of the right femur. Palliative radiotherapy of the right femur was performed. After completing radiotherapy, massive remineralization was seen in the soft tissue component. With the assistance of pre- and post-radiotherapy computerized tomography images, obtained in the process of planning the radiotherapy, we reached the conclusion that in our case the pre-radiotherapy finding was an extreme case of eccentric expansion of the bony cortex due to the outgrowth of bony metastasis. Retrospectively, the initial prominent soft tissue mass associated with the cortical destruction seems to have been a protruding bone metastasis, extending from the medial aspect of the right femur. This peculiar feature with remineralization after radiotherapy should help explain the phenomenon of atypical bony metastasis from a radiological perspective.
Y K Oh; H C Park; Y S Kim
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Japanese journal of clinical oncology     Volume:  31     ISSN:  0368-2811     ISO Abbreviation:  Jpn. J. Clin. Oncol.     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-06-01     Completed Date:  2001-06-07     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0313225     Medline TA:  Jpn J Clin Oncol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  168-71     Citation Subset:  IM    
Department of Therapeutic Radiology, Chosun University Hospital, Chosun University College of Medicine, Kwangju, Republic of Korea.
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MeSH Terms
Adenocarcinoma / secondary*
Bone Neoplasms / radiography*,  radiotherapy,  secondary*
Colonic Neoplasms / pathology*
Fractures, Spontaneous / etiology
Palliative Care*
Soft Tissue Neoplasms / secondary

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