Document Detail


Atypical mycobacterium keratitis associated with penetrating keratoplasty: case report of successful therapy with topical gatifloxacin 0.3%.
MedLine Citation:
PMID:  20164758     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To report successful therapy with gatifloxacin 0.3% ophthalmic solution (Zymar) in a patient with atypical mycobacterium keratitis after penetrating keratoplasty.
METHODS: A 58-year-old patient was referred for evaluation of microbial keratitis after penetrating keratoplasty.
RESULTS: Clinical examination of the patient revealed an infiltrate at the inferior graft-host junction with a satellite lesion with a mild inflammatory reaction in the anterior chamber. Microbiologic evaluation confirmed the diagnosis of atypical mycobacteria keratitis. The corneal abscess was completely eradicated with a topical course of gatifloxacin 0.3% with preservation of graft clarity and good visual acuity. Topical treatment with gatifloxacin 0.3% was continued for an additional period of 5 months.
CONCLUSION: Topical gatifloxacin 0.3% may be successfully used to treat microbial keratitis resulting from atypical mycobacteria.
Authors:
Ana Lilia Perez-Balbuena; Virginia Vanzzini-Zago; Manuel Garza; Diego Cuevas Cancino
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cornea     Volume:  29     ISSN:  1536-4798     ISO Abbreviation:  Cornea     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-10-27     Completed Date:  2011-01-26     Revised Date:  2013-04-24    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  United States    
Other Details:
Languages:  eng     Pagination:  468-70     Citation Subset:  IM    
Affiliation:
Cornea & Refractive Service, Asociación para Evitar la Ceguera en México, Hospital Dr. Luis Sánchez Bulnes, Vicente Garcia Torres, 46 San Lucas Coyoacan, Mexico City, Mexico. albalbuena@prodigy.net.mx
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Anti-Infective Agents / therapeutic use*
Corneal Ulcer / diagnosis,  drug therapy,  etiology*
Eye Infections, Bacterial / diagnosis,  drug therapy,  etiology*
Fluoroquinolones / therapeutic use*
Humans
Keratoplasty, Penetrating / adverse effects*
Male
Middle Aged
Mycobacterium Infections, Nontuberculous / diagnosis,  drug therapy,  etiology*
Mycobacterium chelonae
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 0/Fluoroquinolones; L4618BD7KJ/gatifloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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