Document Detail

Atypical fibroxanthoma with keloidal collagen.
MedLine Citation:
PMID:  20700041     Owner:  NLM     Status:  MEDLINE    
Atypical fibroxanthoma (AFX) is a lesion that typically occurs on actinically damaged skin of the head and neck. Histopathology of these neoplasms reveals atypical cells, which often demonstrate positive staining for immunohistochemical markers such as vimentin and CD10. In the case reported, keloidal collagen was discovered on histopathology. To our knowledge, only rare reports in the literature describe an AFX with similar histopathologic findings, suggesting that this is a distinctive presentation of AFX.
Jacqueline N Fussell; Elizabeth R Cooke; Frances Florentino; Daniel J Sheehan
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  32     ISSN:  1533-0311     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-23     Completed Date:  2011-01-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  713-5     Citation Subset:  IM    
Medical College of Georgia, Augusta, 30904, USA.
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MeSH Terms
Collagen Type I / biosynthesis*
Diabetes Mellitus
Ear / pathology
Histiocytoma, Benign Fibrous / metabolism,  pathology*,  surgery
Hypertension / complications
Kidney Failure, Chronic / complications
Middle Aged
Neprilysin / biosynthesis
Procollagen / biosynthesis*
Renal Dialysis
Skin Neoplasms / metabolism,  pathology*,  surgery
Tumor Markers, Biological / analysis
Reg. No./Substance:
0/Collagen Type I; 0/Procollagen; 0/Tumor Markers, Biological; EC

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