Document Detail

Atypical Ductal Hyperplasia of the Breast Diagnosed by Ultrasonographically Guided Core Needle Biopsy.
MedLine Citation:
PMID:  22161618     Owner:  NLM     Status:  Publisher    
PURPOSE: We analysed the ultrasonographic (US) features of atypical ductal hyperplasia (ADH) of the breast diagnosed by US-guided core needle biopsy (CNB) with the aim of identifying factors that affect the underestimation of ADH. MATERIALS AND METHODS: A total of 134 ADH lesions sampled by US-guided CNB were reviewed retrospectively. All lesions were evaluated for pattern, size, lesion characteristics and margins, and the corresponding surgical outcome or imaging follow-up was obtained. Each patient's clinical and radiological features were analysed to identify factors involved in ADH underestimation. RESULTS: The prevalence of malignancy in each pattern of lesions following surgical excision was 32 / 81 (40 %) for solid masses, 14 / 31 (45 %) for ductal patterns, 5 / 17 (29 %) for complex cystic lesions and 2 / 5 (40 %) for architectural distortions. Based on the results of surgical and US follow-up, none of the category 3 lesions was proven to be a malignancy. Malignancy was found in 17 (21 %) of the 80 BI-RADS (Breast Imaging Reporting and Data System) category 4a lesions, 20 (74 %) of the 27 category 4b lesions, 12 (92 %) of the 13 category 4c lesions, and four (100 %) of the four category 5 lesions. Lesions with a higher US assessment category, lacking circumscribed margins, or a mammographic finding of suspected malignancy were all significantly associated with underestimation (p < 0.05 for each). CONCLUSION: US is useful in evaluating ADH lesions and in clarifying the indication for biopsy of these lesions. Familiarity with the frequency associated with malignancy for each feature will improve the utility of US in the work-up of these breast abnormalities.
H-H Hsu; J-C Yu; G-C Hsu; C-P Yu; W-C Chang; H-J Tung; W-C Lin; S-H Tsai; G-S Huang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-9
Journal Detail:
Title:  Ultraschall in der Medizin (Stuttgart, Germany : 1980)     Volume:  -     ISSN:  1438-8782     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8303585     Medline TA:  Ultraschall Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Department of Radiology, Tri-Service General Hospital, National Defense Medical Center.
Vernacular Title:
Atypische duktale Hyperplasie der Mamma: Diagnose mit der ultraschallgestützten Stanzbiopsie.
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