| Atypical Cushing's syndrome in dogs: arguments for and against. | |
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MedLine Citation:
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PMID: 20219489 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the past 5 to 10 years, much interest has arisen in the syndrome of occult hyperadrenocorticism. Patients with occult hyperadrenocorticism purportedly have many clinical signs and routine laboratory abnormalities suggestive of the presence of typical hyperadrenocorticism, or Cushing's syndrome (ie, hypercortisolism either due to a pituitary or adrenal tumor). However, the standard diagnostic tests-corticotropin (ACTH) stimulation and low-dose dexamethasone suppression tests-are normal. A theory has arisen that the clinical signs of occult hyperadrenocorticism are due to excess adrenal secretion of sex hormones rather than cortisol. The authors believe that the role of sex hormones has not been proven. The article reviews the evidence both for and against the importance of sex hormones in creating occult hyperadrenocorticism. |
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Authors:
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Ellen N Behrend; Robert Kennis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Veterinary clinics of North America. Small animal practice Volume: 40 ISSN: 1878-1306 ISO Abbreviation: Vet. Clin. North Am. Small Anim. Pract. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-11 Completed Date: 2010-06-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7809942 Medline TA: Vet Clin North Am Small Anim Pract Country: United States |
Other Details:
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Languages: eng Pagination: 285-96 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA. behreen@auburn.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenocorticotropic Hormone Aging Alopecia Animals Dexamethasone Dog Diseases / diagnosis*, pathology, therapy Dogs Gonadal Steroid Hormones / metabolism Pituitary ACTH Hypersecretion / diagnosis, therapy, veterinary* Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Gonadal Steroid Hormones; 50-02-2/Dexamethasone; 9002-60-2/Adrenocorticotropic Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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