Document Detail

Atypical Cogan's syndrome: a case report.
MedLine Citation:
PMID:  20015756     Owner:  NLM     Status:  MEDLINE    
Cogan's syndrome is a rare presumed autoimmune disorder characterized by nonsyphilitic interstitial keratitis and progressive audiovestibular symptoms. The initial report by David G. Cogan in 1945 was modified by Haynes et al in 1980 who proposed diagnostic criteria for patients with other ocular or vestibular symptoms and suggested this to be atypical Cogan's syndrome. In a more typical presentation of Cogan's syndrome, ocular and audiovestibular signs and symptoms usually appear alone and are bilateral. We report a case of 50-year-old woman with an atypical Cogan's syndrome manifested by unusual relatively rapid clinical deterioration.
Yu-Lan Mary Ying; Barry E Hirsch
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-06-10
Journal Detail:
Title:  American journal of otolaryngology     Volume:  31     ISSN:  1532-818X     ISO Abbreviation:  Am J Otolaryngol     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000029     Medline TA:  Am J Otolaryngol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  279-82     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Department of Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
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MeSH Terms
Cogan Syndrome / complications,  diagnosis*,  drug therapy
Diagnosis, Differential
Follow-Up Studies
Glucocorticoids / therapeutic use
Hearing Loss, Sensorineural / diagnosis,  etiology*
Magnetic Resonance Imaging
Middle Aged
Tinnitus / diagnosis,  etiology*
Reg. No./Substance:

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