Document Detail


Attractive guidance: how the chemokine SDF1/CXCL12 guides different cells to different locations.
MedLine Citation:
PMID:  22414535     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During the development and adult life of multicellular organisms cells move from one location to another as they assemble into organs, seal a wound or fight pathogens. For navigation, migrating cells follow cues that guide them to their final position. Frequently, a single cue simultaneously guides different cells to different positions. Recent studies of one such cue-the chemokine SDF1-suggest strategies for how the animal achieves this task without causing erroneous migration.
Authors:
Stephen W Lewellis; Holger Knaut
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2012-03-10
Journal Detail:
Title:  Seminars in cell & developmental biology     Volume:  23     ISSN:  1096-3634     ISO Abbreviation:  Semin. Cell Dev. Biol.     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-04     Completed Date:  2012-11-13     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  9607332     Medline TA:  Semin Cell Dev Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  333-40     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Movement*
Chemokine CXCL12 / genetics,  metabolism*
Humans
MicroRNAs / genetics
Grant Support
ID/Acronym/Agency:
HD007520/HD/NICHD NIH HHS; NS069839/NS/NINDS NIH HHS; R01 NS069839/NS/NINDS NIH HHS; R01 NS069839-01A1/NS/NINDS NIH HHS; T32 GM007308/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Chemokine CXCL12; 0/MicroRNAs
Comments/Corrections

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