Document Detail

Attenuating the hypertensive response to laryngoscopy and endotracheal intubation using awake fibreoptic intubation.
MedLine Citation:
PMID:  1539469     Owner:  NLM     Status:  MEDLINE    
Blood pressure and pulse rate measurements were recorded in 35 patients undergoing endotracheal intubation during general anaesthesia (Group A), and 35 patients who had an awake fibreoptic intubation under local anaesthesia (Group B). The mean arterial pressure in Group A rose by a mean of 35 mmHg immediately after intubation, compared with a mean fall of 9 mmHg in Group B. The mean pulse rate in Group A rose by 24 beats per minute (b.p.m.) immediately after intubation, compared with a rise of 3 b.p.m. in Group B. Both these differences were statistically significant (P less than 0.0001 and P less than 0.001 respectively, Mann Whitney U test). Postoperative discomfort was assessed 24 h later by means of linear analogue scales. There was a statistically higher mean score in relation to nose discomfort in Group B (P less than 0.002). Awake fibreoptic intubation successfully reduces the pressor response to endotracheal intubation in normotensive adults. It is suitable for use in those patients who are at risk from the pressor response.
S J Hawkyard; A Morrison; L A Doyle; R S Croton; P N Wake
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  36     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-04-01     Completed Date:  1992-04-01     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  1-4     Citation Subset:  IM    
Department of Surgery, Warrington District General Hospital, Cheshire, UK.
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MeSH Terms
Anesthesia, General
Anesthesia, Local*
Blood Pressure / physiology*
Fiber Optic Technology
Hypertension / physiopathology
Intubation, Intratracheal / methods*
Middle Aged
Pain / etiology
Prospective Studies
Pulse / physiology
Comment In:
Acta Anaesthesiol Scand. 1992 Aug;36(6):601   [PMID:  1482462 ]

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