| Attachment of polymorphonuclear leukocytes to glomeruli in IgA nephropathy. | |
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MedLine Citation:
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PMID: 6349889 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It has been reported that depressed phagocytic activity of polymorphonuclear leukocytes (PMN) and cytoplasmic inclusion bodies containing IgA was observed in PMN from patients with IgA nephropathy. Peripheral blood PMN obtained from 19 patients with IgA nephropathy and 19 healthy subjects is investigated to determine whether or not they adhere to glomeruli in frozen sections of specimens from patients with IgA nephropathy. The average number of PMN from patients with IgA nephropathy that attached to glomeruli was significantly lower than the number seen with PMN obtained from healthy subjects. The results suggest that PMN function is depressed in patients with IgA nephropathy; it is postulated that these abnormalities may play an important role in the pathogenesis and/or progression of IgA nephropathy. |
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Authors:
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M Sato; K Morikawa; S Koshikawa |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical immunology and immunopathology Volume: 29 ISSN: 0090-1229 ISO Abbreviation: Clin. Immunol. Immunopathol. Publication Date: 1983 Oct |
Date Detail:
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Created Date: 1983-10-28 Completed Date: 1983-10-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0356637 Medline TA: Clin Immunol Immunopathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 111-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Autoimmune Diseases / immunology*, pathology Cell Adhesion Child Female Fluorescent Antibody Technique Humans Immunoglobulin A / immunology* Immunoglobulin G / analysis Kidney Diseases / immunology*, pathology Kidney Glomerulus / immunology*, pathology Male Middle Aged Neutrophils / immunology* Phagocytosis |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin A; 0/Immunoglobulin G |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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