Document Detail


Attachment of periodontal ligament cells onto various antibiotics-loaded GTR membranes.
MedLine Citation:
PMID:  16001739     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study compared the natures of various guided tissue regeneration (GTR) membranes impregnated with amoxicillin or tetracycline. Whether the antibiotics-loaded membranes enhance the attachment of the periodontal ligament cells in the presence of oral pathogens was further analyzed. S mutans and A actinomycetemcomitans diminished the attachment of periodontal ligament cells onto the membranes as evaluated by SEM analysis. These bacterial effects on cellular attachment could be reversed using the antibiotics-loaded membranes. The information obtained in this study is valuable for the future application of antibiotics-loaded membranes during GTR therapy.
Authors:
Shan-Ling Hung; Yi-Wen Lin; Yen-Ting Chen; Li-Jane Ling
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The International journal of periodontics & restorative dentistry     Volume:  25     ISSN:  0198-7569     ISO Abbreviation:  Int J Periodontics Restorative Dent     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-07-08     Completed Date:  2005-07-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8200894     Medline TA:  Int J Periodontics Restorative Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  265-75     Citation Subset:  D    
Affiliation:
Institute of Oral Biology, National Yang-Ming University, Taipei, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Actinobacillus actinomycetemcomitans / physiology
Amoxicillin / pharmacology
Analysis of Variance
Anti-Bacterial Agents / pharmacology*
Cell Adhesion / drug effects*
Colony Count, Microbial
Guided Tissue Regeneration, Periodontal*
Membranes, Artificial*
Microbial Sensitivity Tests
Periodontal Ligament / cytology*
Streptococcus mutans / physiology
Tetracycline / pharmacology
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Membranes, Artificial; 26787-78-0/Amoxicillin; 60-54-8/Tetracycline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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