Document Detail

Atrophic change of tongue papilla in 44 patients with Sj?gren syndrome.
MedLine Citation:
PMID:  19464655     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to investigate the atrophic change of tongue papilla in Sj?gren syndrome (SjS) patients and the correlation with characteristic features of the disease. STUDY DESIGN: Atrophic change of tongue papilla, investigated by a digital microscope, was classified from score 0 (normal) to score 6 (severe) and compared among 44 SjS patients, 20 xerostomia patients, and 20 healthy subjects. In SjS patients, correlation of the atrophic score of tongue papilla with characteristic changes in sialometry, sialography, lip biopsy, and serologic tests was also investigated. RESULTS: The atrophic score of tongue papilla was significantly higher in SjS patients and correlated with the decrease of salivary secretion, the stage on sialography, and the histologic grade of the minor salivary gland. CONCLUSION: Atrophic change of tongue papilla is significant in SjS patients and is correlated with the characteristic features of the disease.
Kazuhiko Yamamoto; Miyako Kurihara; Yumiko Matsusue; Yuko Komatsu; Motokatsu Tsuyuki; Takashi Fujimoto; Shinobu Nakamura; Tadaaki Kirita
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  107     ISSN:  1528-395X     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-25     Completed Date:  2009-10-22     Revised Date:  2010-02-11    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  801-5     Citation Subset:  D; IM    
Department of Oral and Maxillofacial Surgery, Nara Medical University, Nara, Japan.
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MeSH Terms
Aged, 80 and over
Case-Control Studies
Middle Aged
Reference Values
Salivation / physiology
Sjogren's Syndrome / pathology*
Taste Buds / pathology
Tongue / pathology*
Xerostomia / pathology*
Comment In:
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jan;109(1):4; author reply 4   [PMID:  19828340 ]

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