Document Detail

Atrioventricular conduction variability in coronary patients.
MedLine Citation:
PMID:  14661167     Owner:  NLM     Status:  MEDLINE    
Variability in atrioventricular (AV) conduction has been described in healthy subjects, whereas data for coronary patients are lacking. This study was designed to evaluate AV conduction variability in patients with stable coronary artery disease. Beat-to-beat PR interval variability with 5-minute resting high-resolution electrocardiogram recordings was measured in 30 men (mean age 50.9 years) with effort angina pectoris and 30 age-matched men without clinically evident coronary artery disease (controls). To evaluate the degree of coronary artery disease in coronary patients, coronary angiography was performed. Coronary patients displayed significantly lower values of PR interval variability compared with control subjects (P <.001). Relative PR variability (PRPP) index, calculated as the ratio of normalized PR variability to cycle length variability, was significantly higher in coronary patients (P =.001) and did depend on the degree of coronary artery disease. We concluded that coronary artery disease is associated with decreased beat-to-beat fluctuations in AV conduction. Increased relative PR variability index suggests inhomogeneous AV conduction in stable coronary atherosclerosis.
Miha Arnol; Vito Starc; Rado Starc
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  36     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-12-08     Completed Date:  2005-06-28     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  311-9     Citation Subset:  IM    
Institute of Physiology, School of Medicine, University of Ljubljana, Slovenia.
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MeSH Terms
Angina Pectoris / physiopathology
Atrioventricular Node / physiopathology*
Coronary Artery Disease / physiopathology*
Heart Conduction System / physiopathology
Middle Aged
Severity of Illness Index

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