Document Detail

Atrioventricular conduction: a determinant for the manifestation of ventricular preexcitation in patients with Wolff-Parkinson-White syndrome.
MedLine Citation:
PMID:  11576154     Owner:  NLM     Status:  MEDLINE    
The relation between the atrioventricular conduction properties of the atrioventricular node and the anterograde conduction ability over the accessory pathway in the Wolff-Parkinson-White syndrome has never been studied. Atrioventricular nodal characteristics were studied in 285 patients with manifest and 204 with concealed accessory pathway who underwent radiofrequency ablation, and compared with 146 controls. First and second degree atrioventricular block was observed in 13 (5%) preexcitation patients after ablation, compared with none in concealed accessory pathway (P=0.001) and control patients (P=0.006). The atrial-His intervals in preexcitation patients (88 +/- 20 ms) was significantly longer than in concealed accessory pathway (76 +/- 15 ms, P<0.0001) and control patients (77 +/- 15 ms, P=0.0007), as was PR intervals (165 +/- 25 versus 149 +/- 20 and 150 +/- 21 ms, P<0.0001, respectively) even after excluding those with atrioventricular block. Significant differences in PR and atrial-His intervals were not observed between concealed accessory pathway and control patients. More preexcitation patients had ventriculoatrial dissociation than had patients in the other groups. The results indicate that atrioventricular block is not uncommon in preexcitation patients and a relatively long atrioventricular conduction time is an electrophysiological prerequisite for the manifestation of preexcitation in the Wolff-Parkinson-White syndrome.
S Liu; S B Olsson; E Hertervig; O Kongstad; S Yuan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical physiology (Oxford, England)     Volume:  21     ISSN:  0144-5979     ISO Abbreviation:  Clin Physiol     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-09-28     Completed Date:  2001-12-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8309768     Medline TA:  Clin Physiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  534-40     Citation Subset:  IM    
Department of Cardiology, University Hospital, Lund University, S-221 85 Lund, Sweden.
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MeSH Terms
Atrioventricular Node / physiopathology*
Catheter Ablation
Heart Block / epidemiology,  etiology
Middle Aged
Neural Conduction
Reference Values
Time Factors
Wolff-Parkinson-White Syndrome / complications,  physiopathology*,  surgery

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