Document Detail

Atrioventricular block pathology in cardiomyopathy by desmin deposition.
MedLine Citation:
PMID:  22323329     Owner:  NLM     Status:  Publisher    
Generally, restrictive cardiomyopathy due to desmin deposition is characterized by restriction to ventricular diastolic filling and different degrees of atrioventricular block (AVB). In this report, we describe the pathological changes of the cardiac conduction system related to AVB. The sinus node, the compact node, and the penetrating bundle (bundle of His) had no abnormalities, however, there was extensive fibrosis of the terminal portions of the branching bundle and the beginning of the left and right bundles at the top of the ventricular septum. The pathogenesis of this fibrous replacement is probably the same that leads to extensive fibrosis of the working ventricular myocardium, and remains to be elucidated.
Luiz Alberto Benvenuti; Vera Dermarchi Aiello; Breno Alencar Araripe Falcão; Silvia Gelás Lage
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Publication Detail:
Journal Detail:
Title:  Arquivos brasileiros de cardiologia     Volume:  98     ISSN:  1678-4170     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-2-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421031     Medline TA:  Arq Bras Cardiol     Country:  -    
Other Details:
Languages:  SPA; ENG; POR     Pagination:  e3-e6     Citation Subset:  -    
Instituto do Coração, Hospital das Clínicas, FMUSP, São Paulo, SP, Brasil.
Vernacular Title:
Patologia do bloqueio atrioventricular na cardiomiopatia por depósito de desmina.
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