| Atrioventricular valve annulus velocity and acceleration during global hypoxia in newborn pigs - assessment of myocardial function. | |
| | |
MedLine Citation:
|
PMID: 19713716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Global hypoxia may affect regions of the neonatal heart during systole and diastole differently. OBJECTIVE: In the first study, the aim was to assess longitudinal myocardial function in newborn pigs during global hypoxia and recovery. In the second study, invasive hemodynamic data were evaluated and compared with tissue velocities and acceleration. METHODS: Myocardial Doppler measurements of velocity and acceleration in the atrioventricular valve annuli during global hypoxia were made. Results: In the first experiment, systolic velocity (S), early diastolic velocity (E') and peak systolic acceleration (pSac) decreased during hypoxia. S, pSac and E'(mva) (mitral valve annulus) recovered after reoxygenation, while E'(septal) and E'(tva) (tricuspid valve annulus) did not. Isovolumic acceleration (IVA) did not reflect systolic dysfunction. In the second experiment, S(mva) and pSac(mva) declined during hypoxia similarly to maximum dP/dT. E'(mva) and E'(tva) were correlated with tau and both changed parallel to minimum dP/dT. In the TVA maximum dP/dT and pSac(tva) did not change, while S(tva) declined. By correcting for heart rate the pattern of alteration in S and pSac became comparable to the changes in E'. CONCLUSION: Tissue Doppler velocity in systole, diastole and acceleration during rapid ejection reflect hemodynamic changes in the neonatal myocardium during global hypoxia and recovery. S and pSac reflect systolic function, while E' correlates with tau and mirrors diastolic function. |
| | |
Authors:
|
Hans Henrik Odland; Grete A B Kro; Thor Edvardsen; Erik Thaulow; Ola Didrik Saugstad |
Related Documents
:
|
19920046 - Automated segmentation of routine clinical cardiac magnetic resonance imaging for asses... 17313636 - Correlation of tei index obtained from tissue doppler echocardiography with invasive me... 9110196 - Normal values and reproducibility of left ventricular filling parameters by radionuclid... 22356536 - The psychology of earthquake induced stress cardiomyopathy, myocardial infarction and n... 17481946 - Clinical trials update from the american college of cardiology 2007: alpha, everest, fu... 7994256 - Cardiac arrhythmia after infusion of cryopreserved stem cells. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-08-28 |
Journal Detail:
|
Title: Neonatology Volume: 97 ISSN: 1661-7819 ISO Abbreviation: Neonatology Publication Date: 2010 |
Date Detail:
|
Created Date: 2010-02-05 Completed Date: 2010-04-22 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101286577 Medline TA: Neonatology Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 100-7 Citation Subset: IM |
Copyright Information:
|
Copyright 2009 S. Karger AG, Basel. |
Affiliation:
|
Department of Pediatric Research, Rikshospitalet University Hospital, Oslo, Norway. h.h.odland@medisin.uio.no |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Animals, Newborn Anoxia / physiopathology*, ultrasonography Diastole / physiology Disease Models, Animal Echocardiography, Doppler Heart Rate / physiology Linear Models Mitral Valve / physiopathology*, ultrasonography Myocardial Contraction / physiology* Recovery of Function / physiology Stroke Volume / physiology Swine Systole / physiology Tricuspid Valve / physiopathology*, ultrasonography Ventricular Pressure / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: peptide receptor radi...
Next Document: Transcriptional Control of Cytokine Release from Monocytes of the Newborn: Effects of Endogenous and...