Document Detail

Atrial and ventricular arryhthmogenic potential in Turner Syndrome.
MedLine Citation:
PMID:  18834465     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: P-wave dispersion (Pd), corrected P-wave dispersion (Pdc), QT-wave dispersion (QTd), and corrected QT-wave dispersion (QTdc) parameters were not assessed in Turner Syndrome (TS) before. The aim of this study is to investigate the cardiac arrhythmogenic potential in patients with TS. METHODS: Thirty-one patients with TS and 30 healthy women were enrolled in the study. For this purpose 12-lead electrocardiogram (ECG) and 24-hour ambulatory ECG recordings were performed. RESULTS: Pd, Pdc, QTd, and QTdc were significantly higher in patients with TS. On 24-hour ambulatory ECG recording, the mean heart rate (HR) was higher, while the mean of all RR intervals between normal beats (MeanNN), the standard deviation of all the RR intervals (SDNN), the square root of the mean of the squared differences of two consecutive RR intervals (rMSSD), and the percentage of the beats with consecutive RR interval difference more than 50 milliseconds (pNN50) were lower in TS. CONCLUSION: There were significant increases in Pd, Pdc, QTd, and QTdc in patients with TS and they may be features of the disease. The frequency of supraventricular arrhythmias was increased. There also was a significant deterioration of sympathetic and parasympathetic components of autonomic function as assessed by heart rate variability (HRV) in Turner patients.
Ahmet B Sozen; Kivanç Cefle; Hasan Kudat; Sukru Ozturk; Huseyin Oflaz; Burak Pamukcu; Vakur Akkaya; Pinar Isguven; Sukru Palanduz; Mustafa Ozcan; Taner Goren; Ozen Guven
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  31     ISSN:  1540-8159     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-10-06     Completed Date:  2009-01-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1140-5     Citation Subset:  IM    
Department of Cardiology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey.
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MeSH Terms
Atrial Fibrillation / diagnosis*,  physiopathology*
Electrocardiography, Ambulatory / statistics & numerical data
Heart Rate*
Turner Syndrome / diagnosis*,  physiopathology*
Ventricular Fibrillation / diagnosis*,  physiopathology*
Young Adult

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