Document Detail

Atrial septal defect closure on cardiopulmonary bypass in a sickle cell anemia: role of hydroxyurea and partial exchange transfusion.
MedLine Citation:
PMID:  20442545     Owner:  NLM     Status:  MEDLINE    
Partial exchange transfusion during cardiopulmonary bypass, while conducting cardiac surgery may be a useful technique in patients with high level of sickle hemoglobin. Along with this preoperative use of hydroxyurea and alternative analgesic modalities such as transcutaneous electrical nerve stimulation in postoperative period may be beneficial, in our opinion. A 16-year-old female of Turner's syndrome having sickle cell anemia scheduled for closure of arterial septal defect on cardiopulmonary bypass was managed with partial exchange transfusion and warm cardioplegia.
Kundan Sandugir Gosavi; Sananta Kumar Dash; Bharat N Shah; C B Upasani
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of cardiac anaesthesia     Volume:  13     ISSN:  0974-5181     ISO Abbreviation:  Ann Card Anaesth     Publication Date:    2010 May-Aug
Date Detail:
Created Date:  2010-05-05     Completed Date:  2010-11-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815987     Medline TA:  Ann Card Anaesth     Country:  India    
Other Details:
Languages:  eng     Pagination:  145-7     Citation Subset:  IM    
Department of Anesthesia and Critical Care, Grant Medical College and Sir JJ Hospital, Mumbai, India.
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MeSH Terms
Anemia, Sickle Cell / therapy*
Antisickling Agents / therapeutic use*
Blood Transfusion / methods*
Cardiopulmonary Bypass / methods*
Heart Arrest, Induced / methods
Heart Septal Defects, Atrial / surgery*
Hydroxyurea / therapeutic use*
Treatment Outcome
Reg. No./Substance:
0/Antisickling Agents; 127-07-1/Hydroxyurea

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