Document Detail

Atrial pacing in patients with sinus node dysfunction.
MedLine Citation:
PMID:  984067     Owner:  NLM     Status:  MEDLINE    
Sinus nod recovery time (SNRT) at paced atrial rates of 100 (SNRT100) and 120 (SNRT120) beats/min, atrial effective refractory periods at spontaneous heart rates (AERP) and at paced rates of 100 (AERP100) and 120 (AERP120) beats/min, and premature atrial stimulation were among the studies in evaluating 33 patients with symptomatic sinus node disease and 42 normal subjects. Although mean SNRT100 and SNRT120 were statistically significantly greater in patients than in control subjects, there was a significant overlap between patient and control groups, and SNRT100 or SNRT120 was associated with a 30.3 per cent false-negative and 5 per cent false-positive incidence. Correction for heart rate (SNRT-spontaneous cycle length) failed to improve the sensitivity or specificity of this test. There was no significant difference in mean AERP, AERP100 or AERP120, or in sinoatrial conduction time in patients compared with control subjects. Analyses of curves derived from plots of test and return cycles showed abnormal curves in only five of the 24 patients studied by progressively premature atrial stimulation. Two of these five patients showed normal zone I and II phenomena followed by a progressive linear increase in the return cycle that was thought to be due to abnormal refractoriness of the perinodal fibers.
M M Scheinman; F W Kunkel; R W Peters; D S Hirschfeld; P L Schoenfeld; J A Abbott; G Modin
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of medicine     Volume:  61     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1976 Nov 
Date Detail:
Created Date:  1977-01-03     Completed Date:  1977-01-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  641-9     Citation Subset:  AIM; IM    
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MeSH Terms
Arrhythmia, Sinus / physiopathology*
Heart Rate
Middle Aged
Pacemaker, Artificial*
Refractory Period, Electrophysiological
Sinoatrial Node / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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