Document Detail

Atrial natriuretic peptide release due to physical exercise in healthy persons and in cardiac patients.
MedLine Citation:
PMID:  2951559     Owner:  NLM     Status:  MEDLINE    
Plasma levels of human atrial natriuretic peptide were determined during different stages of a symptom-limited bicycle ergometer stress test. Eight healthy persons and three patients suffering from well-defined cardiac disorders were examined. Measurements of the peptide were performed before the exercise, at 75 watts, at maximal work load, and 10 and 30 min after ceasing the exercise. In healthy persons plasma levels of the peptide increased from preexercise levels of 4-41 ng/l to 16-59 ng/l at maximal work load, but remained in the normal range (10-70 ng/l). In contrast, in the cardiac patients, levels of the peptide were up to 8-fold higher at maximal physical exertion (154-270 ng/l) than at rest (34-86 ng/l). Within a recovery period of 30 min hormone concentrations returned almost to preexercise levels.
D H Petzl; E Hartter; W Osterode; H Böhm; W Woloszczuk
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Klinische Wochenschrift     Volume:  65     ISSN:  0023-2173     ISO Abbreviation:  Klin. Wochenschr.     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-05-21     Completed Date:  1987-05-21     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  2985205R     Medline TA:  Klin Wochenschr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  194-6     Citation Subset:  IM    
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MeSH Terms
Atrial Natriuretic Factor / blood*
Heart Aneurysm / blood
Heart Failure / blood*
Heart Septal Defects, Ventricular / blood
Hypertension / blood*
Middle Aged
Myocardial Infarction / blood
Physical Exertion*
Reg. No./Substance:
85637-73-6/Atrial Natriuretic Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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