| Atrial fibrillation and stroke. Three new studies, three remaining questions. | |
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MedLine Citation:
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PMID: 8017999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three new studies help clarify important clinical issues regarding antithrombotic therapy for stroke prevention in patients with atrial fibrillation. The European Atrial Fibrillation Trial compared the efficacy of oral anticoagulation, aspirin, and placebo for stroke prevention in patients with atrial fibrillation with a recent stroke or transient ischemic attack. The results of the Stroke Prevention in Atrial Fibrillation II trial, which compared the efficacy of warfarin and aspirin, provide new information regarding the risk of intracranial hemorrhage in elderly patients with atrial fibrillation. Finally, an analysis of pooled data from the first five randomized trials identified clinical features that are predictive of stroke risk in individual patients with atrial fibrillation. These studies address unanswered questions regarding atrial fibrillation and stroke and have significant implications for patient management. |
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Authors:
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G W Albers |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Archives of internal medicine Volume: 154 ISSN: 0003-9926 ISO Abbreviation: Arch. Intern. Med. Publication Date: 1994 Jul |
Date Detail:
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Created Date: 1994-07-28 Completed Date: 1994-07-28 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1443-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurology and Neurological Sciences, Stanford University Medical Center, Palo Alto, Calif. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anticoagulants
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therapeutic use* Aspirin / therapeutic use Atrial Fibrillation / complications, drug therapy* Cerebrovascular Disorders / etiology, prevention & control* Clinical Trials as Topic Humans Risk Factors Warfarin / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 50-78-2/Aspirin; 81-81-2/Warfarin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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