Document Detail

Atrial fibrillation in patients hospitalized for congestive heart failure: the same prognostic influence independently of left ventricular systolic function?
MedLine Citation:
PMID:  16297467     Owner:  NLM     Status:  MEDLINE    
Atrial fibrillation (AF) was described to be associated with an adverse prognosis in several studies of heart failure (HF). However, it is not clear whether it directly increased mortality or is only a marker for severity of HF. AIMS: To determine the influence of AF on mortality of HF patients distinguishing between patients with preserved and deteriorated systolic function (SF). METHOD AND RESULTS: 1636 patients who, between 1991 and 2002 had been hospitalized in a Cardiology Service for HF, were studied. Survival (SV) data (mean follow-up time: 3.14 years) has shown that there was no difference in SV between patients with (540 patients of the whole group) and without AF in the group with preserved SF (presented in 38.7% of cases), however, in the group of patients with deteriorated SF (AF presented in 31.0% of cases), SV time was significantly (p=0.01) shorter among patients with AF, this association being independent of age, sex, aetiology, risk factors, clinical signs and pharmacological treatment; relative risk: 1.831(1.120-2.994). CONCLUSION: AF is more prevalent among HF patients with preserved SF than among those with deteriorated SF, but only increases the risk of death among the latter.
Lilian Grigorian Shamagian; Alfonso Varela Roman; Javier Garcia Seara; Jose Luis Martinez Sande; Pedro Rigueiro Veloso; José Ramón Gonzalez-Juanatey
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Publication Detail:
Type:  Journal Article     Date:  2005-11-16
Journal Detail:
Title:  International journal of cardiology     Volume:  110     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-12     Completed Date:  2006-11-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  366-72     Citation Subset:  IM    
Servicio de Cardiologia, Hospital Clinico Universitario, Santiago de Compostela, Spain.
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MeSH Terms
Atrial Fibrillation / complications*,  diagnosis*,  pathology
Follow-Up Studies
Heart Failure / complications*,  diagnosis*,  pathology
Survival Rate
Ventricular Function, Left / physiology*

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