Document Detail

Atrial fibrillation in incident dialysis patients.
MedLine Citation:
PMID:  19494800     Owner:  NLM     Status:  MEDLINE    
Despite the importance of cardiovascular disease in dialysis patients, the frequency of atrial fibrillation in incident dialysis patients has not been determined. We analyzed the prevalence of atrial fibrillation in patients starting dialysis over a 4-year period, its occurrence over the course of dialysis, and its influence on ischemic stroke and mortality. Factors predisposing to atrial fibrillation were noted, as was the influence of arrhythmia on mortality and presentation of ischemic stroke. Of the 256 patients studied, 31 had atrial fibrillation at the start of dialysis. Increased age, larger left atrium, and female gender were independently related to the presence of atrial fibrillation at dialysis inception. Of the 225 patients who were in sinus rhythm at the start of dialysis, 28 developed atrial fibrillation during a mean follow-up time of 2 years. The presence of valvular calcifications, bundle branch block, previous ischemic stroke, lower ejection fraction, higher pulse pressure, and lower hemoglobin concentration were predictors of the clinical evolution of atrial fibrillation. Overall, atrial fibrillation increased mortality risk 1.72-fold and ischemic stroke risk 9.8-fold. Therefore, it appears that atrial fibrillation is quite prevalent and its presence is associated with significant risk.
Eduardo Vazquez; Carmen Sanchez-Perales; Francisco Garcia-Garcia; Patricia Castellano; Maria-Jose Garcia-Cortes; Antonio Liebana; Cristobal Lozano
Publication Detail:
Type:  Journal Article     Date:  2009-06-03
Journal Detail:
Title:  Kidney international     Volume:  76     ISSN:  1523-1755     ISO Abbreviation:  Kidney Int.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-11-11     Completed Date:  2010-01-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0323470     Medline TA:  Kidney Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  324-30     Citation Subset:  IM    
Division of Cardiology, Department of Cardiology, Complejo Hospitalario de Jaen, Jaen, Spain.
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MeSH Terms
Aged, 80 and over
Atrial Fibrillation / epidemiology*
Brain Ischemia / complications
Kidney Failure, Chronic / mortality*,  therapy
Middle Aged
Prospective Studies
Renal Dialysis
Spain / epidemiology
Stroke / epidemiology,  etiology
Survival Analysis
Comment In:
Kidney Int. 2009 Aug;76(3):247-9   [PMID:  19904256 ]

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